STAPLED PEPTIDES AND METHODS THEREOF

Among other things, the present disclosure provides various agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologie...

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Bibliographische Detailangaben
Hauptverfasser: LI, Zhi, CONRADY, Deborah, Gail, MCGEE, John, Hanney, CAPPUCCI, Sarah, Isabelle, WHITE, Brian, Halbert, ZHANG, Yue-Mei, ALFARO-LOPEZ, Lorenzo, Josue, TREMBLAY, Martin, Robert, SI, Yaguang, JEWETT, Ivan, Tucker
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Among other things, the present disclosure provides various agents. In some embodiments, provided agents can bind to beta-catenin. In some embodiments, the present disclosure provides technologies for modulating beta-catenin functions. In some embodiments, the present disclosure provides technologies for preventing and/or treating conditions, disorders or diseases associated with beta-catenin. In some embodiments, the present disclosure provides designed amino acids which can provide improved properties and/or activities. In some embodiments, the present disclosure provides agents comprising such amino acids.