PYRIMIDINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF AGAINST MYCOBACTERIUM TUBERCULOSIS INFECTION

PYRIMIDINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF AGAINST MYCOBACTERIUM TUBERCULOSIS INFECTION

Provided are a pyrimidinone derivative, and a preparation method therefor and the use thereof against Mycobacterium tuberculosis infection. The structure of the pyrimidinone derivative is represented by formula I. Experiments prove that the pyrimidinone derivative has obvious anti-Mycobacterium tube...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LIU, Yishuang, MENG, Jianzhou, SUN, Lianqi, LI, Zhuorong
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided are a pyrimidinone derivative, and a preparation method therefor and the use thereof against Mycobacterium tuberculosis infection. The structure of the pyrimidinone derivative is represented by formula I. Experiments prove that the pyrimidinone derivative has obvious anti-Mycobacterium tuberculosis activity and is particularly suitable for preparing a drug for preventing and/or treating related diseases caused by Mycobacterium tuberculosis.