METHOD FOR PRODUCING 2-(HALOGENATED METHYL)NAPHTHALENE AND 2-NAPHTHYL ACETONITRILE
2-(Halogenated methyl)naphthalenes and 2-naphthylacetonitrile are produced safely and inexpensively with high selectivity in good yield.2-(Halogenated methyl)naphthalenes are produced by halogenation of 2-methylnaphthalene using a reaction with a halogenating agent under light irradiation, in a solv...
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Zusammenfassung: | 2-(Halogenated methyl)naphthalenes and 2-naphthylacetonitrile are produced safely and inexpensively with high selectivity in good yield.2-(Halogenated methyl)naphthalenes are produced by halogenation of 2-methylnaphthalene using a reaction with a halogenating agent under light irradiation, in a solvent selected from a halogenated hydrocarbon, an aliphatic ester and an aliphatic hydrocarbon. The compounds are derived into various pharmaceuticals or their intermediates (for example, 2-naphthylacetonitrile). |
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