MANNOSE RECEPTOR-DERIVED PEPTIDES FOR NEUTRALIZING PORE-FORMING TOXINS FOR THERAPEUTIC USES

MANNOSE RECEPTOR-DERIVED PEPTIDES FOR NEUTRALIZING PORE-FORMING TOXINS FOR THERAPEUTIC USES

A polypeptide or peptidomimetic comprising a sequence of at least 7 residues differing by residue substitutions, deletions or insertions numbering 0-2 compared to the sequence: GLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPT-MSWNDINCEHLNNWICQ (SEQ ID NO: 1), for use as a medicament, in particular in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SOTIRIOU, Georgios, SUBRAMANIAM, Karthik, HENRIQUES NORMARK, Birgitta
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:A polypeptide or peptidomimetic comprising a sequence of at least 7 residues differing by residue substitutions, deletions or insertions numbering 0-2 compared to the sequence: GLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPT-MSWNDINCEHLNNWICQ (SEQ ID NO: 1), for use as a medicament, in particular in pneumococcal disease.