VACCINE COMBINATION AGAINST RESPIRATORY SYNCYTIAL VIRUS INFECTION

VACCINE COMBINATION AGAINST RESPIRATORY SYNCYTIAL VIRUS INFECTION

Methods of safely inducing a protective immune response against respiratory syncytial virus (RSV) and methods of preventing infection and/or replication of RSV in human subjects are described. The methods include administering to the subjects (a) an effective amount of an adenoviral vector encoding...

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Bibliographische Detailangaben
Hauptverfasser: HEIJNEN, Esther, Mathilde, Eugene, Wilhelmus, ZAHN, Roland, Christian, DE PAEPE, Els, CALLENDRET, Benoit, C.,S, COMEAUX, Christy, Ann
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Methods of safely inducing a protective immune response against respiratory syncytial virus (RSV) and methods of preventing infection and/or replication of RSV in human subjects are described. The methods include administering to the subjects (a) an effective amount of an adenoviral vector encoding a recombinant RSV F protein that is stabilized in a pre-fusion conformation, and (b) an effective amount of an RSV F protein that is stabilized in a pre-fusion conformation.