METHODS OF EVALUATING MICRO RNA

Provided are methods of quantifying miRNA in skin, the method comprising: applying a swellable microprotrusion array to a region of skin to absorb interstitial fluid; removing the microprotrusion array; recovering miRNA from the interstitial fluid absorbed into the microprotrusion array; and quantif...

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Bibliographische Detailangaben
Hauptverfasser: DONNELLY, Ryan F, MANGEZ, Claire, BRUN, Cécilia, ISON, Renny, ROUX, Pierre-François
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided are methods of quantifying miRNA in skin, the method comprising: applying a swellable microprotrusion array to a region of skin to absorb interstitial fluid; removing the microprotrusion array; recovering miRNA from the interstitial fluid absorbed into the microprotrusion array; and quantifying the miRNA. Also provided are methods of monitoring epigenetic changes in skin using a swellable microprotrusion array.