USE OF JUNIPER (JUNIPERUS COMMUNIS) BERRIES EXTRACT, DEOXYPODOPHYLLOTOXIN AND AGATHADIOL, AS POSITIVE ALLOSTERIC MODULATORS OF CANNABINOID TYPE 1 RECEPTOR

It is disclosed a Juniperus communis extract comprising agathadiol, and pharmaceutical compositions comprising said extract, for use in the prevention and/or treatment of a disease or condition responsive to positive allosteric modulators (PAM) of cannabinoid type 1 receptor (CB 1R). Additionally, d...

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Bibliographische Detailangaben
Hauptverfasser: MUÑOZ BLANCO, Eduardo, UNCITI BROCETA, Juan Diego, APPENDINO, Giovanni Battista, POLLASTRO, Federica
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:It is disclosed a Juniperus communis extract comprising agathadiol, and pharmaceutical compositions comprising said extract, for use in the prevention and/or treatment of a disease or condition responsive to positive allosteric modulators (PAM) of cannabinoid type 1 receptor (CB 1R). Additionally, disclosed is agathadiol, as well as pharmaceutical compositions comprising the same, for use in the prevention and/or treatment of a disease or condition responsive to positive allosteric modulators cannabinoid type 1 receptor. Finally, also disclosed are nutraceutical compositions comprising agathadiol, or a Juniperus communis extract comprising the same, for preventing or alleviating the symptoms of a disease or condition responsive to positive allosteric modulators cannabinoid type 1 receptor.