C-TYPE NATRIURETIC PEPTIDES AND METHODS THEREOF IN TREATING CANCER

The present disclosure relates to methods of treating a subject having abnormal vasculature by administering to the subject a therapeutically effective bolus dose of a composition including a long acting C-type natriuretic peptide (CNP), CNP derivative, long acting CNP derivative, long acting CNP re...

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Bibliographische Detailangaben
Hauptverfasser: KUMAZOE, Motofumi, NISHIMOTO-ASHFIELD, Akiko, YAO, Yao, NOJIRI, Takashi, TANAKA, Yasutake, CASTILLO, Gerardo, TACHIBANA, Hirofumi, BOLOTIN, Elijah
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates to methods of treating a subject having abnormal vasculature by administering to the subject a therapeutically effective bolus dose of a composition including a long acting C-type natriuretic peptide (CNP), CNP derivative, long acting CNP derivative, long acting CNP receptor (NPRB) agonist, or any combination thereof. The present disclosure further relates to treating a subject in need of an increase in cytotoxic T cell and/or NK cell activity by administering to the subject a therapeutically effective bolus dose of a composition including a long acting C-type natriuretic peptide (CNP), CNP derivative, long acting CNP derivative, long acting CNP receptor (NPRB) agonist, or any combination thereof.