NUCLEIC ACID CONSTRUCT, RECOMBINANT INFLUENZA VIRUS, METHOD FOR PREPARING A RECOMBINANT INFLUENZA VIRUS, COMPOSITION AND USE

The present invention relates to a nucleic acid construct, a recombinant multiply-defective influenza virus, that promotes expression of an immunomodulatory protein in a host. This is applicable to the development of vaccines against infectious diseases, particularly those caused by influenza virus...

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Hauptverfasser: XAVIER, Marcelo, Pascoal, MACHADO, Alexandre, de Magalhães, Vieira, PEREIRA, Igor, A, ARAÚJO, Márcio, Sobreira, Silva, ALVES, Pedro Augusto, CARDOSO, Kimberly, Freitas, MESSIAS, Sarah, Giarola, da Silva, FAUSTINO, Lídia Paula, GONÇALVES, Ana Paula, de Faria, DE PAULA, Ianca Évelyn, Silva, TAVARES, Luciana, Pádua, DE CARVALHO, Ketyllen, Reis, Andrade
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a nucleic acid construct, a recombinant multiply-defective influenza virus, that promotes expression of an immunomodulatory protein in a host. This is applicable to the development of vaccines against infectious diseases, particularly those caused by influenza virus and Coronavirus.