MRNA OR MRNA COMPOSITION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Provided are an mRNA or an mRNA composition, and an mRNA vaccine comprising the mRNA or the mRNA composition. The mRNA or the mRNA composition comprises an mRNA sequence encoding an S protein of a novel coronavirus SARS-CoV-2 or a variant thereof, and an mRNA sequence encoding an RBD in the S protei...

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Bibliographische Detailangaben
Hauptverfasser: LI, Junqiang, YU, Xuefeng, CHAO, Shoubai, LI, Jin, SHAO, Zhongqi, ZHU, Tao, SHEN, Chunlin, YAN, Qiaoling, WANG, Haomeng
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided are an mRNA or an mRNA composition, and an mRNA vaccine comprising the mRNA or the mRNA composition. The mRNA or the mRNA composition comprises an mRNA sequence encoding an S protein of a novel coronavirus SARS-CoV-2 or a variant thereof, and an mRNA sequence encoding an RBD in the S protein or a variant thereof. Further provided are the applications of the mRNA or the mRNA composition, and the mRNA vaccine comprising the mRNA or the mRNA composition in preparation of a medication for preventing and/or treating a disease caused by a novel coronavirus SARS-CoV-2 infection.