CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION
Flavone derivatives and pharmaceutical compositions including the derivatives are disclosed. In some instances, the compounds have increased aqueous solubility, bioavailability, and ability to cross the blood-brain-barrier. The compounds may be used to inhibit CK2 activity and/or to treat diseases a...
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Zusammenfassung: | Flavone derivatives and pharmaceutical compositions including the derivatives are disclosed. In some instances, the compounds have increased aqueous solubility, bioavailability, and ability to cross the blood-brain-barrier. The compounds may be used to inhibit CK2 activity and/or to treat diseases and conditions mediated at least in part by CK2 enzyme. |
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