METHODS FOR THE TREATMENT OF NUCLEOTIDE REPEAT EXPANSION DISORDERS ASSOCIATED WITH MSH3 ACTIVITY

The present disclosure features useful compositions and methods to treat repeat expansion disorders (e.g., trinucleotide repeat expansion disorders), in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with...

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Bibliographische Detailangaben
Hauptverfasser:	BIALEK, Peter Edward, BERMINGHAM, Nessan Anthony, BETTENCOURT, Brian R
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure features useful compositions and methods to treat repeat expansion disorders (e.g., trinucleotide repeat expansion disorders), in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with MSH3 activity.