CANCER ANTIGEN FOR EARLY CANCER DETECTION

The invention relates to obtaining, isolating and detecting a new marker of epithelial cancers. A method comprises obtaining biological samples from patients with suspected malignant neoplasms of the epithelium and from a control group of healthy subjects. Next, a new marker of epithelial cancers th...

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Hauptverfasser: MORO-VIDAL, Ricardo, CHERKASOVA, Janneta Rashidovna, TSURKAN, Sergei Alexandrovich, KONDRATIEV, Vyacheslav Borisovich
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to obtaining, isolating and detecting a new marker of epithelial cancers. A method comprises obtaining biological samples from patients with suspected malignant neoplasms of the epithelium and from a control group of healthy subjects. Next, a new marker of epithelial cancers that forms on the surface of cancer cells of epithelial origin is isolated. If the level of expression of the epithelial cancer marker in the samples obtained from the patients exceeds the level of expression of the marker in the samples obtained from healthy subjects, then the result indicates a high probability that epithelial cancer is present. The cancer antigen is a family of N-glycoproteins that have identical N-glycosylation and have a molecular mass of 55-85 kD. The detection method includes a capture reagent for the indicated cancer antigen, a detection reagent and a detection reagent.