ARYL OR HETEROARYL DERIVATIVE
A compound indicated by formula (I) or a pharmacologically acceptable salt thereof is provided as a compound that can be a therapeutic or prophylactic drug for TRPC6-related diseases, such as nephrotic syndrome, membranous nephropathy, acute renal failure, septicemia, chronic renal failure, diabetic...
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creator | MINAMIZONO, Kunio HOSODA, Shinnosuke SUGIYAMA, Sakae JOHNSON, Brett M MARUYAMA, Akinobu ZHAO, Wei KAWANA, Asahi YOKOSAKA, Takuya KANEKO, Toshiyuki KATO, Kenta TAKEUCHI, Susumu CHAKKA, Nagasree SASAKI, Kosuke WHITE, Ryan d KOSHIMIZU, Masaki |
description | A compound indicated by formula (I) or a pharmacologically acceptable salt thereof is provided as a compound that can be a therapeutic or prophylactic drug for TRPC6-related diseases, such as nephrotic syndrome, membranous nephropathy, acute renal failure, septicemia, chronic renal failure, diabetic nephropathy, pulmonary hypertension, acute lung injury, heart failure, malignant tumor, and muscular dystrophy. (In the formula, Ar1, Ar2, X1-X3, R1, R3, R7, R8, L1, and L2 are as defined in the specifications.) |
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(In the formula, Ar1, Ar2, X1-X3, R1, R3, R7, R8, L1, and L2 are as defined in the specifications.)</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230222&DB=EPODOC&CC=EP&NR=4137481A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230222&DB=EPODOC&CC=EP&NR=4137481A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MINAMIZONO, Kunio</creatorcontrib><creatorcontrib>HOSODA, Shinnosuke</creatorcontrib><creatorcontrib>SUGIYAMA, Sakae</creatorcontrib><creatorcontrib>JOHNSON, Brett M</creatorcontrib><creatorcontrib>MARUYAMA, Akinobu</creatorcontrib><creatorcontrib>ZHAO, Wei</creatorcontrib><creatorcontrib>KAWANA, Asahi</creatorcontrib><creatorcontrib>YOKOSAKA, Takuya</creatorcontrib><creatorcontrib>KANEKO, Toshiyuki</creatorcontrib><creatorcontrib>KATO, Kenta</creatorcontrib><creatorcontrib>TAKEUCHI, Susumu</creatorcontrib><creatorcontrib>CHAKKA, Nagasree</creatorcontrib><creatorcontrib>SASAKI, Kosuke</creatorcontrib><creatorcontrib>WHITE, Ryan d</creatorcontrib><creatorcontrib>KOSHIMIZU, Masaki</creatorcontrib><title>ARYL OR HETEROARYL DERIVATIVE</title><description>A compound indicated by formula (I) or a pharmacologically acceptable salt thereof is provided as a compound that can be a therapeutic or prophylactic drug for TRPC6-related diseases, such as nephrotic syndrome, membranous nephropathy, acute renal failure, septicemia, chronic renal failure, diabetic nephropathy, pulmonary hypertension, acute lung injury, heart failure, malignant tumor, and muscular dystrophy. 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(In the formula, Ar1, Ar2, X1-X3, R1, R3, R7, R8, L1, and L2 are as defined in the specifications.)</abstract><oa>free_for_read</oa></addata></record> |
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language | eng ; fre ; ger |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | ARYL OR HETEROARYL DERIVATIVE |
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