ARYL OR HETEROARYL DERIVATIVE

A compound indicated by formula (I) or a pharmacologically acceptable salt thereof is provided as a compound that can be a therapeutic or prophylactic drug for TRPC6-related diseases, such as nephrotic syndrome, membranous nephropathy, acute renal failure, septicemia, chronic renal failure, diabetic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MINAMIZONO, Kunio, HOSODA, Shinnosuke, SUGIYAMA, Sakae, JOHNSON, Brett M, MARUYAMA, Akinobu, ZHAO, Wei, KAWANA, Asahi, YOKOSAKA, Takuya, KANEKO, Toshiyuki, KATO, Kenta, TAKEUCHI, Susumu, CHAKKA, Nagasree, SASAKI, Kosuke, WHITE, Ryan d, KOSHIMIZU, Masaki
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A compound indicated by formula (I) or a pharmacologically acceptable salt thereof is provided as a compound that can be a therapeutic or prophylactic drug for TRPC6-related diseases, such as nephrotic syndrome, membranous nephropathy, acute renal failure, septicemia, chronic renal failure, diabetic nephropathy, pulmonary hypertension, acute lung injury, heart failure, malignant tumor, and muscular dystrophy. (In the formula, Ar1, Ar2, X1-X3, R1, R3, R7, R8, L1, and L2 are as defined in the specifications.)