METHODS AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF AN ANTI-B-CORONAVIRUS ANTIBODY IN A SAMPLE

METHODS AND KITS FOR DETECTING OR DETERMINING AN AMOUNT OF AN ANTI-B-CORONAVIRUS ANTIBODY IN A SAMPLE

Disclosed herein are methods, kits, systems, algorithms and improvements for detecting the presence of or determining an amount, quantity, concentration and/or level of an antibody against at least one type of β-coronavirus, such as, for example, an antibody against SARS-CoV or SARS-CoV-2, in one or...

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Hauptverfasser: TRUDEAU, Beth C, COLLER, Kelly, MACDONALD, Patrick, MATIAS, Matthew S, KAR, Alak, PEARCE, Sandra K, RUAN, Qiaoqiao, GALLI, Claudio, GARDINER, Mary E, HAWKSWORTH, David, MAROHNIC, Chris, BELIGERE, Gangamani S, SCHULTZ, Philip W, TU, Bailin, STEWART, James L, HARTNETT, James, TETIN, Sergey Y, GRIESHABER, Jessica L, BIEGALSKI, Thomas T, PALAFOX, Mary Ann P, BRENNAN, Melissa B, MUTHUSAMY, Saminathan X, CASSIDY, Michael S, JIAO, Weijie, ZHANG, Yangrong E, STROBEL, Carolyn, TAYLOR, Russell E, OTIS, Kathy, LIN, Zhihong, TIEMAN, Bryan, MOORE, Jeff, DAGHFAL, David J, WIEBE, Peter, PROSTKO, John C, FRIAS, Edwin C, MUERHOFF, A. Scott, CLOHERTY, Gavin A, ZIEMANN, Robert, MEYER, Todd, RODGERS, Mary A
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Zusammenfassung:Disclosed herein are methods, kits, systems, algorithms and improvements for detecting the presence of or determining an amount, quantity, concentration and/or level of an antibody against at least one type of β-coronavirus, such as, for example, an antibody against SARS-CoV or SARS-CoV-2, in one or more samples obtained from a subject. In some aspects, the methods, kits and systems relate to detecting the presence of or determining an amount, quantity, concentration and/or level of at least one type of anti-β-coronavirus antibody, such as an IgG and/or IgM antibody, in one or more samples obtained from a subject. The methods, kits systems, algorithms and improvements can also be used to monitor a subject's response and/or treatment to a β-coronavirus, determine whether or not a subject will develop or experience a cytokine storm, predict outcome in a subject, determine whether a subject can be administered a vaccine for a β-coronavirus, monitoring antibody response in individuals that have received a β-coronavirus vaccine (such as a SARS-CoV-2 vaccine), and/or determine the immune status of a subject.