ELECTROSPRAY CURRENT MEASUREMENT IN THE NANOSPRAY AND MICROSPRAY REGIME

An electrospray ionization system used in mass spectrometry provides for improved current measurement. The system includes a fluid union (224), a fluid column (208) coupled with a first port (238) of the fluid union, a power source (202, 504) coupled with the fluid union and configured to apply a vo...

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Bibliographische Detailangaben
Hauptverfasser:	POLTASH, Michael L, LINDSETH, Dale, MINKLER, David E, SILVEIRA, Joshua A, WOUTERS, Eloy R
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BASIC ELECTRIC ELEMENTS ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS ELECTRICITY MEASURING MEASURING ELECTRIC VARIABLES MEASURING MAGNETIC VARIABLES PHYSICS TESTING
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Beschreibung
Zusammenfassung:	An electrospray ionization system used in mass spectrometry provides for improved current measurement. The system includes a fluid union (224), a fluid column (208) coupled with a first port (238) of the fluid union, a power source (202, 504) coupled with the fluid union and configured to apply a voltage potential to the fluid union, and an electrospray emitter (232, 234, 506) coupled with a second port of the fluid union. The power source is coupled with the first port and configured to apply the voltage potential to the first port to restrict current leakage from the fluid union. The current sensing circuit (206, 500) is configured to determine an electrical current flow between the power source and the at least one of the fluid union and the first port.