NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR
Provided are a novel derivative of β-apopicropodophyllin and a method of preparing the same, and more particularly, a compound represented by Formula 1 below, which is a novel derivative of β-apopicropodophyllin derived from podophyllotoxin, which is an anticancer agent, a method of preparing the sa...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NAM, So-Yeon HYUN, Se-Hee CHOI, Jong-Ryoo CHOI, In-Young |
| description | Provided are a novel derivative of β-apopicropodophyllin and a method of preparing the same, and more particularly, a compound represented by Formula 1 below, which is a novel derivative of β-apopicropodophyllin derived from podophyllotoxin, which is an anticancer agent, a method of preparing the same, and a composition for treating cancer, which includes the compound.In Formula 1, R is a C2 to C10 alkyl group, a Cz to C10 alkyl group containing an allyl- or alkyne, a -[CH2]n-C3 to C8 cycloalkyl group, a substituted or unsubstituted -[CH2]n-phenyl group, a substituted or unsubstituted -[CH2]n-C5 to C6 heteroaromatic group, a -C(=O)-Ci to C8 alkyl group, a substituted or unsubstituted -C(=O)-[CH2]n-phenyl group, or a substituted or unsubstituted -C(=O)-[CH2]n-C5 to C6 heteroaromatic group, wherein n is an integer of 0 to 6. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4130008A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4130008A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4130008A13</originalsourceid><addsrcrecordid>eNqNyrEKwjAQANAsDqL-w_1AIaUOrmdzIYGYO44QcCpF4iRaqP-PDn6A01ve1qTMlRI40lixxErAHs5UsENhiaOysGMJ15RiBswORElQv5czXKgEdlACKXnWvdnc58faDj93BjyVMXRteU1tXeZbe7b3RHLsB2vtCfvhj_IBjLct1w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR</title><source>esp@cenet</source><creator>NAM, So-Yeon ; HYUN, Se-Hee ; CHOI, Jong-Ryoo ; CHOI, In-Young</creator><creatorcontrib>NAM, So-Yeon ; HYUN, Se-Hee ; CHOI, Jong-Ryoo ; CHOI, In-Young</creatorcontrib><description>Provided are a novel derivative of β-apopicropodophyllin and a method of preparing the same, and more particularly, a compound represented by Formula 1 below, which is a novel derivative of β-apopicropodophyllin derived from podophyllotoxin, which is an anticancer agent, a method of preparing the same, and a composition for treating cancer, which includes the compound.In Formula 1, R is a C2 to C10 alkyl group, a Cz to C10 alkyl group containing an allyl- or alkyne, a -[CH2]n-C3 to C8 cycloalkyl group, a substituted or unsubstituted -[CH2]n-phenyl group, a substituted or unsubstituted -[CH2]n-C5 to C6 heteroaromatic group, a -C(=O)-Ci to C8 alkyl group, a substituted or unsubstituted -C(=O)-[CH2]n-phenyl group, or a substituted or unsubstituted -C(=O)-[CH2]n-C5 to C6 heteroaromatic group, wherein n is an integer of 0 to 6.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230208&DB=EPODOC&CC=EP&NR=4130008A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230208&DB=EPODOC&CC=EP&NR=4130008A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NAM, So-Yeon</creatorcontrib><creatorcontrib>HYUN, Se-Hee</creatorcontrib><creatorcontrib>CHOI, Jong-Ryoo</creatorcontrib><creatorcontrib>CHOI, In-Young</creatorcontrib><title>NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR</title><description>Provided are a novel derivative of β-apopicropodophyllin and a method of preparing the same, and more particularly, a compound represented by Formula 1 below, which is a novel derivative of β-apopicropodophyllin derived from podophyllotoxin, which is an anticancer agent, a method of preparing the same, and a composition for treating cancer, which includes the compound.In Formula 1, R is a C2 to C10 alkyl group, a Cz to C10 alkyl group containing an allyl- or alkyne, a -[CH2]n-C3 to C8 cycloalkyl group, a substituted or unsubstituted -[CH2]n-phenyl group, a substituted or unsubstituted -[CH2]n-C5 to C6 heteroaromatic group, a -C(=O)-Ci to C8 alkyl group, a substituted or unsubstituted -C(=O)-[CH2]n-phenyl group, or a substituted or unsubstituted -C(=O)-[CH2]n-C5 to C6 heteroaromatic group, wherein n is an integer of 0 to 6.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQANAsDqL-w_1AIaUOrmdzIYGYO44QcCpF4iRaqP-PDn6A01ve1qTMlRI40lixxErAHs5UsENhiaOysGMJ15RiBswORElQv5czXKgEdlACKXnWvdnc58faDj93BjyVMXRteU1tXeZbe7b3RHLsB2vtCfvhj_IBjLct1w</recordid><startdate>20230208</startdate><enddate>20230208</enddate><creator>NAM, So-Yeon</creator><creator>HYUN, Se-Hee</creator><creator>CHOI, Jong-Ryoo</creator><creator>CHOI, In-Young</creator><scope>EVB</scope></search><sort><creationdate>20230208</creationdate><title>NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR</title><author>NAM, So-Yeon ; HYUN, Se-Hee ; CHOI, Jong-Ryoo ; CHOI, In-Young</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4130008A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>NAM, So-Yeon</creatorcontrib><creatorcontrib>HYUN, Se-Hee</creatorcontrib><creatorcontrib>CHOI, Jong-Ryoo</creatorcontrib><creatorcontrib>CHOI, In-Young</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NAM, So-Yeon</au><au>HYUN, Se-Hee</au><au>CHOI, Jong-Ryoo</au><au>CHOI, In-Young</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR</title><date>2023-02-08</date><risdate>2023</risdate><abstract>Provided are a novel derivative of β-apopicropodophyllin and a method of preparing the same, and more particularly, a compound represented by Formula 1 below, which is a novel derivative of β-apopicropodophyllin derived from podophyllotoxin, which is an anticancer agent, a method of preparing the same, and a composition for treating cancer, which includes the compound.In Formula 1, R is a C2 to C10 alkyl group, a Cz to C10 alkyl group containing an allyl- or alkyne, a -[CH2]n-C3 to C8 cycloalkyl group, a substituted or unsubstituted -[CH2]n-phenyl group, a substituted or unsubstituted -[CH2]n-C5 to C6 heteroaromatic group, a -C(=O)-Ci to C8 alkyl group, a substituted or unsubstituted -C(=O)-[CH2]n-phenyl group, or a substituted or unsubstituted -C(=O)-[CH2]n-C5 to C6 heteroaromatic group, wherein n is an integer of 0 to 6.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP4130008A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T10%3A55%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NAM,%20So-Yeon&rft.date=2023-02-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4130008A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |