OLIGONUCLEOTIDES COMPRISING A PHOSPHOROTRITHIOATE INTERNUCLEOSIDE LINKAGE

The present invention relates to an oligonucleotide comprising at least one phosphorotrithioate internucleoside linkage of formula (I)wherein (A1), (A2) and R are as defined in the description and in the claim. The oligonucleotide of the invention can be used as a medicament.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LI, Meiling, DUSCHMALÉ, Joerg Jakob Andreas, SCHAEUBLIN, Adrian, BLEICHER, Konrad, KOCH, Troels, KOLLER, Erich, DUSCHMALÉ, Martina Brigitte
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to an oligonucleotide comprising at least one phosphorotrithioate internucleoside linkage of formula (I)wherein (A1), (A2) and R are as defined in the description and in the claim. The oligonucleotide of the invention can be used as a medicament.