VARICELLA ZOSTER VIRUS FUSION PROTEIN AND IMMUNOGENIC COMPOSITION COMPRISING SAME

The present invention relates to a Varicella zoster virus fusion protein and an immunogenic composition comprising same and, more specifically, to a fusion protein comprising the glycoprotein E (gE) of Varicella zoster virus (VZV) and a constant region of an immunoglobulin molecule, and an immunogen...

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Bibliographische Detailangaben
Hauptverfasser: KIM, Pan Kyeom, KIM, Min Soo, NOH, Han Mi, PARK, Geun Soo, RYU, Dong Kyun, SHIM, Eun Yeong, LEE, Soo Young, LA, Wan Geun
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a Varicella zoster virus fusion protein and an immunogenic composition comprising same and, more specifically, to a fusion protein comprising the glycoprotein E (gE) of Varicella zoster virus (VZV) and a constant region of an immunoglobulin molecule, and an immunogenic composition comprising same. The present invention not only remarkably increases a Varicella zoster virus-specific cell-mediated immune response, but also exhibits the effect of rapidly and potently inducing an immune response and sustaining the immune response for a long period of time, compared to preexisting vaccines, thereby can be usefully used to prevent Varicella zoster-related diseases.