METHODS OF MAKING CHIMERIC ANTIGEN RECEPTOR-EXPRESSING CELLS

The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.

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Bibliographische Detailangaben
Hauptverfasser: GUIMARAES, Carla, KOSHY, Sandeep Tharian, BROGDON, Jennifer, JAYASHANKAR, Shyamali, STEIN, Andrew Marc, KODRASI, Olja, TREANOR, Louise, LIM, Hyungwook, PRATICO, Elizabeth Dorothy, PRICE, Andrew, YANG, Jennifer, GRANDA, Brian Walter, DRANOFF, Glenn, GREENE, Michael R, RAYO, Amy, ZHU, Xu, MILLER, Sandra, CEBE, Regis, HACK, Anniesha, ENGELS, Boris, SOHONI, Akash, BONDANZA, Attilio, BARDROFF, Michael
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention provides methods of making immune effector cells (for example, T cells, NK cells) that express a chimeric antigen receptor (CAR), and compositions generated by such methods.