ARYL HYDANTOIN HETEROCYCLES AND METHODS OF USE

ARYL HYDANTOIN HETEROCYCLES AND METHODS OF USE

Disclosed is a compound of formula (I) in which R1, R2, R3, X1, X2, X2′, X3, X4, ring A, m, n, and o are as described herein. The compound of formula (I) is useful for treating a disorder associated with androgen receptor malfunction, such as a hyperproliferative disorder, in a subject in need there...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FIGG, SR., William Douglas, TAPADAR, Subhasish, OYELERE, Adegboyega K, GRYDER, Berkley E, STROPE, Jonathan D
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed is a compound of formula (I) in which R1, R2, R3, X1, X2, X2′, X3, X4, ring A, m, n, and o are as described herein. The compound of formula (I) is useful for treating a disorder associated with androgen receptor malfunction, such as a hyperproliferative disorder, in a subject in need thereof.