HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF

The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable sa...

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Bibliographische Detailangaben
Hauptverfasser:	HUANG, Xiangui, SHEN, Weichao, YAN, Qingyan, BIE, Pingyan, YE, Cheng, CAO, Hai, XING, Qingna, WU, Nuoyi, HU, Taishan, GUO, Yanghui, CAO, Qi, LI, Wenpeng, CHEN, Lei, WANG, Xin, QIU, Zongxing, LIAO, Weiwei, MENG, Lichen
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable salt, and use thereof as a therapeutic agent, in partucular, as an SHP2 allosteric inhibitor, wherein the definition of substituents in general formula (AI) is the same as that in the description.