ANTIFIBROTIC AGENT, AND METHOD FOR PRODUCING EXTRACELLULAR VESICLES HAVING ANTIFIBROTIC ACTION

An object of the present invention is to provide a therapeutic preparation composed of a population of extracellular vesicles having a high therapeutic effect, particularly to provide an anti-fibrosis agent. The present invention relates to the anti-fibrosis agent containing a mesenchymal stem cell-...

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Bibliographische Detailangaben
Hauptverfasser: YAMANE Masayuki, ISHIDOME Takamasa
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An object of the present invention is to provide a therapeutic preparation composed of a population of extracellular vesicles having a high therapeutic effect, particularly to provide an anti-fibrosis agent. The present invention relates to the anti-fibrosis agent containing a mesenchymal stem cell-derived extracellular vesicle, as an active ingredient, in which an extracellular vesicle is obtained by a method of using a substance that contains an extracellular vesicle having an affinity for phosphatidylserine, or/and an extracellular vesicle is derived from a mesenchymal stem cell stimulated with fibroblast growth factor, and relates to a method of producing an extracellular vesicle as the anti-fibrosis agent.