GRANULES CONTAINING POSACONAZOLE

GRANULES CONTAINING POSACONAZOLE

The present invention relates to granules prepared by subjecting a mixture containing posaconazole, an enteric polymer and a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle size distribution and contain the drug in molecularly dispersed form, and a gastro-res...

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Hauptverfasser: PRATHAP, Vamshi Ramana, FITZNER, Ansgar, ZOUBARI, Gaith, RALLABANDI, Bala Ramesha Chary, VELCHURI, Srikanth, KALAMATA, Venkatasimhadri Naidu, MADALLAPALLI, Kiran Kumar
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator PRATHAP, Vamshi Ramana
FITZNER, Ansgar
ZOUBARI, Gaith
RALLABANDI, Bala Ramesha Chary
VELCHURI, Srikanth
KALAMATA, Venkatasimhadri Naidu
MADALLAPALLI, Kiran Kumar
description The present invention relates to granules prepared by subjecting a mixture containing posaconazole, an enteric polymer and a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle size distribution and contain the drug in molecularly dispersed form, and a gastro-resistant, optionally film-coated tablet prepared from the granules.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title GRANULES CONTAINING POSACONAZOLE
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