GRANULES CONTAINING POSACONAZOLE

The present invention relates to granules prepared by subjecting a mixture containing posaconazole, an enteric polymer and a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle size distribution and contain the drug in molecularly dispersed form, and a gastro-res...

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Bibliographische Detailangaben
Hauptverfasser:	PRATHAP, Vamshi Ramana, FITZNER, Ansgar, ZOUBARI, Gaith, RALLABANDI, Bala Ramesha Chary, VELCHURI, Srikanth, KALAMATA, Venkatasimhadri Naidu, MADALLAPALLI, Kiran Kumar
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to granules prepared by subjecting a mixture containing posaconazole, an enteric polymer and a non-enteric polymer to hot-melt extrusion, whereby the granules have a specific particle size distribution and contain the drug in molecularly dispersed form, and a gastro-resistant, optionally film-coated tablet prepared from the granules.