MEK INHIBITORS AND THERAPEUTIC USES THEREOF

MEK INHIBITORS AND THERAPEUTIC USES THEREOF

The present disclosure provides compounds, compositions containing such compounds, and methods of designing, developing, producing and preparing compounds represented by general Formula (I), including pharmaceutically acceptable salts thereof or a synthetic intermediate thereof:The compounds act as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: POELAKKER, Jarno, LEENDERS, Ruben, DECORTE, Bart Lieven, FOWLER, Kevin, KOLITZ, Sarah, HALL, Brett Matthew, FOLMER, Rutger Henk Adriaan, KING, Peter John, DOODEMAN, Robin, WEGERT, Anita
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present disclosure provides compounds, compositions containing such compounds, and methods of designing, developing, producing and preparing compounds represented by general Formula (I), including pharmaceutically acceptable salts thereof or a synthetic intermediate thereof:The compounds act as MEK inhibitors and are capable of displaying one or more beneficial therapeutic effects, including treating cancer.