SYSTEMS AND METHODS FOR IMPROVED AUTOMATION OF LABORATORY PROCESSES

Methods and devices are provided for computer implemented improvement of process performance of automated laboratory protocols that typically require at least one liquid handling step that is performed by using a liquid handling apparatus under the operative control of a processor. The methods comprise: i. defining at least one liquid handling step in the protocol that comprises a liquid handling operation; ii. selecting at least a first and at least a second process factors for the at least one liquid handling step in the protocol, wherein the first and second process factors are different and are selected from the group consisting of: an equipment process factor; a liquid process factor; and a protocol process factor; iii. assigning parameter variations for the first and second process factors selected for investigation; iv. performing a plurality of test runs on the liquid handling apparatus to determine the effects of the parameter variations for the first and second process factors; v. analysing the results of the plurality of test runs to identify the one or more test runs that show optimal process performance; and vi. amending the automated laboratory protocol to improve process performance of the liquid handling apparatus.