DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS

The present invention relates to dihydrocyclopenta-isoquinoline-sulfonamide derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain...

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Hauptverfasser: ROWLEY, Julian Hugh, HASLETT, Gregory William, LALLEMAND, Benedicte, MONCK, Nathaniel Julius Thomas, NORMAN, Timothy John, PHILPS, Oliver, YOUSUF, Zeshan, CONNELLY, Rickki Lee, TRANI, Giancarlo, MADDEN, James, BYRNE, Douglas, MEARS, Richard John, HEER, Jag Paul, RAMPALAKOS, Konstantinos, SUGANTHAN, Selvaratnam
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to dihydrocyclopenta-isoquinoline-sulfonamide derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the FcεRI receptor.