ANTISENSE GUIDE RNA WITH ADDED FUNCTIONAL REGION FOR EDITING TARGET RNA

Problem: Providing antisense guide RNA for editing target RNA by ADAR. Solution: Antisense guide RNA, for editing target RNA by ADAR, wherein: at least one functional region and an antisense region that is complementary to part of the target RNA and forms a double strand with the target RNA are incl...

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Hauptverfasser: YOSHIMI, Eiji, MANDA, Mariko, MORIYA, Yukari, ARAI, Takatomo, GOTOH, Takayasu
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Problem: Providing antisense guide RNA for editing target RNA by ADAR. Solution: Antisense guide RNA, for editing target RNA by ADAR, wherein: at least one functional region and an antisense region that is complementary to part of the target RNA and forms a double strand with the target RNA are included; and the at least one functional region is joined to the antisense region and substantially does not include an ADAR-recruiting base sequence. Representative drawing: None