HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP

HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP

A novel compound having HDAC2 inhibitory activity is provided.A compound represented by Formula (I):wherein the group represented by Formula:is a group represented by Formula:or the like, wherein R3 is each independently amino or the like, and n is an integer of 0 to 4, X1 is N or the like, X2 is N...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: YAMAKAWA Hidekuni, TAKAYA Kenji, YOSHIHARA Ken, ANAN Kosuke, MIZOTE Keisuke, KAI Hiroyuki, NAKAHARA Kenji
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator YAMAKAWA Hidekuni
TAKAYA Kenji
YOSHIHARA Ken
ANAN Kosuke
MIZOTE Keisuke
KAI Hiroyuki
NAKAHARA Kenji
description A novel compound having HDAC2 inhibitory activity is provided.A compound represented by Formula (I):wherein the group represented by Formula:is a group represented by Formula:or the like, wherein R3 is each independently amino or the like, and n is an integer of 0 to 4, X1 is N or the like, X2 is N or the like, R4 and R5 are each independently a hydrogen atom or the like, R1 is substituted with Substituent group C or unsubstituted non-aromatic carbocyclyl or the like, Substituent group C is halogen or the like, and R2 is a hydrogen atom,or a pharmaceutically acceptable salt thereof.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP4074700A4</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP4074700A4</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP4074700A43</originalsourceid><addsrcrecordid>eNqNikEKwjAQAHPxIOof8oFCwEDPa7omC3W3pKvQUykST6KF-n9U8AGehhlmbTRRr8JoG4SAOrTQoyVOdCCVbBNciKNl0iwRuQrCCsTfBllOoBRsQsUsYQjtR2KWc7c1q9t0X8rux42xR9SQqjI_x7LM07U8ymvEzrva186B3_-xvAELnTAw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP</title><source>esp@cenet</source><creator>YAMAKAWA Hidekuni ; TAKAYA Kenji ; YOSHIHARA Ken ; ANAN Kosuke ; MIZOTE Keisuke ; KAI Hiroyuki ; NAKAHARA Kenji</creator><creatorcontrib>YAMAKAWA Hidekuni ; TAKAYA Kenji ; YOSHIHARA Ken ; ANAN Kosuke ; MIZOTE Keisuke ; KAI Hiroyuki ; NAKAHARA Kenji</creatorcontrib><description>A novel compound having HDAC2 inhibitory activity is provided.A compound represented by Formula (I):wherein the group represented by Formula:is a group represented by Formula:or the like, wherein R3 is each independently amino or the like, and n is an integer of 0 to 4, X1 is N or the like, X2 is N or the like, R4 and R5 are each independently a hydrogen atom or the like, R1 is substituted with Substituent group C or unsubstituted non-aromatic carbocyclyl or the like, Substituent group C is halogen or the like, and R2 is a hydrogen atom,or a pharmaceutically acceptable salt thereof.</description><language>eng ; fre ; ger</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240207&amp;DB=EPODOC&amp;CC=EP&amp;NR=4074700A4$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20240207&amp;DB=EPODOC&amp;CC=EP&amp;NR=4074700A4$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YAMAKAWA Hidekuni</creatorcontrib><creatorcontrib>TAKAYA Kenji</creatorcontrib><creatorcontrib>YOSHIHARA Ken</creatorcontrib><creatorcontrib>ANAN Kosuke</creatorcontrib><creatorcontrib>MIZOTE Keisuke</creatorcontrib><creatorcontrib>KAI Hiroyuki</creatorcontrib><creatorcontrib>NAKAHARA Kenji</creatorcontrib><title>HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP</title><description>A novel compound having HDAC2 inhibitory activity is provided.A compound represented by Formula (I):wherein the group represented by Formula:is a group represented by Formula:or the like, wherein R3 is each independently amino or the like, and n is an integer of 0 to 4, X1 is N or the like, X2 is N or the like, R4 and R5 are each independently a hydrogen atom or the like, R1 is substituted with Substituent group C or unsubstituted non-aromatic carbocyclyl or the like, Substituent group C is halogen or the like, and R2 is a hydrogen atom,or a pharmaceutically acceptable salt thereof.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNikEKwjAQAHPxIOof8oFCwEDPa7omC3W3pKvQUykST6KF-n9U8AGehhlmbTRRr8JoG4SAOrTQoyVOdCCVbBNciKNl0iwRuQrCCsTfBllOoBRsQsUsYQjtR2KWc7c1q9t0X8rux42xR9SQqjI_x7LM07U8ymvEzrva186B3_-xvAELnTAw</recordid><startdate>20240207</startdate><enddate>20240207</enddate><creator>YAMAKAWA Hidekuni</creator><creator>TAKAYA Kenji</creator><creator>YOSHIHARA Ken</creator><creator>ANAN Kosuke</creator><creator>MIZOTE Keisuke</creator><creator>KAI Hiroyuki</creator><creator>NAKAHARA Kenji</creator><scope>EVB</scope></search><sort><creationdate>20240207</creationdate><title>HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP</title><author>YAMAKAWA Hidekuni ; TAKAYA Kenji ; YOSHIHARA Ken ; ANAN Kosuke ; MIZOTE Keisuke ; KAI Hiroyuki ; NAKAHARA Kenji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP4074700A43</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>YAMAKAWA Hidekuni</creatorcontrib><creatorcontrib>TAKAYA Kenji</creatorcontrib><creatorcontrib>YOSHIHARA Ken</creatorcontrib><creatorcontrib>ANAN Kosuke</creatorcontrib><creatorcontrib>MIZOTE Keisuke</creatorcontrib><creatorcontrib>KAI Hiroyuki</creatorcontrib><creatorcontrib>NAKAHARA Kenji</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YAMAKAWA Hidekuni</au><au>TAKAYA Kenji</au><au>YOSHIHARA Ken</au><au>ANAN Kosuke</au><au>MIZOTE Keisuke</au><au>KAI Hiroyuki</au><au>NAKAHARA Kenji</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP</title><date>2024-02-07</date><risdate>2024</risdate><abstract>A novel compound having HDAC2 inhibitory activity is provided.A compound represented by Formula (I):wherein the group represented by Formula:is a group represented by Formula:or the like, wherein R3 is each independently amino or the like, and n is an integer of 0 to 4, X1 is N or the like, X2 is N or the like, R4 and R5 are each independently a hydrogen atom or the like, R1 is substituted with Substituent group C or unsubstituted non-aromatic carbocyclyl or the like, Substituent group C is halogen or the like, and R2 is a hydrogen atom,or a pharmaceutically acceptable salt thereof.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre ; ger
recordid cdi_epo_espacenet_EP4074700A4
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title HISTONE DEACETYLASE INHIBITOR HAVING NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T10%3A08%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YAMAKAWA%20Hidekuni&rft.date=2024-02-07&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP4074700A4%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true