HUMANIZED CLDN18.2 ANTIBODIES

The invention provides humanized antibodies binding to CLDN18.2 with a high affinity. Further, the antibodies do not exhibit cross-reactivity to CLDN18.1. The invention also provides nucleic acids, vectors, host cells and medical uses.

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Bibliographische Detailangaben
Hauptverfasser: BAMMERT, Lukas, WALDMEIER, Lorenz, BEERLI, Roger, MOEBIUS, Ulrich, KYRYCH SADILKOVA, Lenka
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The invention provides humanized antibodies binding to CLDN18.2 with a high affinity. Further, the antibodies do not exhibit cross-reactivity to CLDN18.1. The invention also provides nucleic acids, vectors, host cells and medical uses.