SUBSTITUTED NUCLEOSIDE ANALOGS AS PRMT5 INHIBITORS

The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating dis...

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Bibliographische Detailangaben
Hauptverfasser:	GUDADE, Ganesh, Bhausaheb, YADAV, Amol, Maruti, KULKARNI, Chaitanya, Prabhakar, SINDKHEDKAR, Milind, Dattatraya, KAMBOJ, Rajender, Kumar, BHAGWAT, Shankar, Bhaskar, NAIR, Prathap, Sreedharan, PALLE, Venkata, P
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.