PLASMID ENCODING B-CELL ACTIVATING FACTOR RECEPTOR (BAFF-R) AND USES OF SAME IN THE TREATMENT AND PREVENTION OF INFLAMMATORY DISEASES IN FISH

The present invention relates to a plasmid that encodes a fusion protein comprising a signal peptide and the extracellular domain of the B-cell activating factor receptor (BAFF-R), and optionally, a fragment of the constant region (Fc) of an immunoglobulin. The invention also relates to compositions...

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Bibliographische Detailangaben
Hauptverfasser: HOLLAND, Jason W, MUÑOZ ATIENZA, Estefanía, FABER, Marc, TAFALLA PIÑEIRO, Carolina, SECOMBES, Christopher J
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a plasmid that encodes a fusion protein comprising a signal peptide and the extracellular domain of the B-cell activating factor receptor (BAFF-R), and optionally, a fragment of the constant region (Fc) of an immunoglobulin. The invention also relates to compositions comprising said plasmid, and to the use of same in the treatment and/or prevention of inflammatory diseases in fish, more preferably in salmonids.