IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF

IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF

The present invention relates to a group of compounds with a tricyclic core based on imidazo[1,2-b]pyridazine of formula (I):which are inhibitors of HASPIN, whose activity is required for the proliferation of certain tumoral cells, so the compounds of the invention are useful for the prevention and/...

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Bibliographische Detailangaben
Hauptverfasser: BLANCO APARICIO, Carmen, PASTOR FERNÁNDEZ, Joaquín, RODRÍGUEZ ARÍSTEGUI, Sonsoles, CEBRIÁ GÓMEZ, Antonio, GÓMEZ DE LA OLIVA, Cristina Ana, ALBARRÁN SANTIÑO, María Isabel, GARCÍA GARCÍA, Ana Belén, MARTÍNEZ GONZÁLEZ, Sonia
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to a group of compounds with a tricyclic core based on imidazo[1,2-b]pyridazine of formula (I):which are inhibitors of HASPIN, whose activity is required for the proliferation of certain tumoral cells, so the compounds of the invention are useful for the prevention and/or treatment of cancer.