MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND RELATED METHODS

The invention provides non-naturally occurring microbial organisms comprising a 1,4-utanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expression of BDO. The invention addition...

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Bibliographische Detailangaben
Hauptverfasser: Burk, Mark J, Pujol-Baxley, Catherine J, Niu, Wei, Trawick, John D, Osterhout, Robin E, Yim, Harry, Van Dien, Stephen J, Haselbeck, Robert, Burgard, Anthony P, Sun, Jun
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention provides non-naturally occurring microbial organisms comprising a 1,4-utanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO.