MICRO-RNA COMPOSITION FUNCTIONALIZED FOR DENTAL IMPLANTS

The invention is directed to the medical field, and more particularly to a titanium dental implant functionalized with a selected combination of miR-140-3p, miR-145-5p, miR-146a-5p, and miR-195-5p inhibitors. Under the influence of miRNA inhibitors, the integration of the dental implant into the bon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Snipaitiene, Kristina, Punceviciene, Egle, Butrimiene, Irena, Jarmalaite, Sonata, Puriene, Alina, Rovas, Adomas
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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Beschreibung
Zusammenfassung:	The invention is directed to the medical field, and more particularly to a titanium dental implant functionalized with a selected combination of miR-140-3p, miR-145-5p, miR-146a-5p, and miR-195-5p inhibitors. Under the influence of miRNA inhibitors, the integration of the dental implant into the bone is accelerated, thus reducing the likelihood of dental implant failure and reducing the need for systemic antibacterial drugs. Also, due to more effective osseointegration, the dental implant can be used in patients with predisposed conditions - diabetes, osteoporosis, thyroid dysfunction.