FLUORESCENCE MICROSCOPE SYSTEM AND METHOD

A fluorescence microscope system (100) for imaging a sample (102) comprising at least two different fluorophores comprises an illumination system (104) configured to emit illumination light for exciting the fluorophores, and an optical detection system (112) configured to generate images of the sample (102) based on fluorescence light emitted by the excited fluorophores. The fluorescence microscope system (100) further comprises a control unit (124) configured to determine whether to image the sample (102) in a concurrent imaging mode or in a sequential imaging mode based on at least one characteristic of each of the different fluorophores and based on at least one parameter of the optical detection system (112) and/or at least one parameter of the illumination system (104). In the concurrent imaging mode, the different fluorophores are imaged simultaneously. In the sequential imaging mode, the different fluorophores are divided into a first group and at least one second group, and the fluorophores of the first and second groups are imaged subsequently.