METHOD FOR SEPARATING AND DETECTING EXOSOMES, AND KIT FOR SEPARATION AND DETECTION THEREOF

METHOD FOR SEPARATING AND DETECTING EXOSOMES, AND KIT FOR SEPARATION AND DETECTION THEREOF

What is provided is a method for separation and detection of exosomes, the method including: a complex formation step of bringing a biological sample into contact with a capture molecule, the capture molecule including a specific binding substance for an antigen expressed on a cancer cell surface, t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YAGUCHI, Tomonori, KAWAKAMI, Yutaka, WAKUI, Seiki
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:What is provided is a method for separation and detection of exosomes, the method including: a complex formation step of bringing a biological sample into contact with a capture molecule, the capture molecule including a specific binding substance for an antigen expressed on a cancer cell surface, to form a complex of an exosome and the capture molecule; and a detection step of bringing the complex into contact with a detector molecule, the detector molecule including a specific binding substance for an antigen expressed on a cancer cell surface and a labeling substance, to detect the complex by using the detector molecule, in which the antigen expressed on a cancer cell surface for at least one of the capture molecule and the detector molecule is cell-surface vimentin.