SOLID PHARMACEUTICAL FORMULATIONS COMPRISING TICAGRELOR

The present invention relates to a pharmaceutical composition, comprising ticagrelor, wherein the pharmaceutical composition is in a solid dosage form with improved pharmaceutical characteristics. Solid dosage form comprising ticagrelor and pharmaceutically acceptable excipients manufactured by usin...

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Bibliographische Detailangaben
Hauptverfasser: AKTAS, Tansel, KANIK, Bayram, YILDIRIM, Ersin, ÖZTÜRK, Fatma
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a pharmaceutical composition, comprising ticagrelor, wherein the pharmaceutical composition is in a solid dosage form with improved pharmaceutical characteristics. Solid dosage form comprising ticagrelor and pharmaceutically acceptable excipients manufactured by using wet granulation method wherein; the composition comprises microcrystalline cellulose, and silicon dioxide together in the extragranular phase in weight ratio of microcrystalline cellulose : silicon dioxide is between 35:1 to 45:1.