ARTIFICIAL GENE AND GENE MUTATION METHOD

An artificial gene has a 15N abundance exceeding a natural abundance in bases of at least a portion of DNA. A method for mutating a gene includes a first step of producing a state in which 15N is unevenly distributed into a prescribed DNA in a living cell; and a second step of irradiation with a pro...

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Hauptverfasser: MORIOKA, Ryo, SUZUKI, Iwane, IWATA, Yasushi, TOMITA, Kanako, YANG, Tianjing
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An artificial gene has a 15N abundance exceeding a natural abundance in bases of at least a portion of DNA. A method for mutating a gene includes a first step of producing a state in which 15N is unevenly distributed into a prescribed DNA in a living cell; and a second step of irradiation with a proton beam at an energy at which the 15N produces a resonant nuclear reaction.