BIOMARKERS FOR ANTI-TIGIT ANTIBODY TREATMENT

Novel methods for selecting a patient with a cancer for treatment with a TIGIT antagonist are disclosed. The methods employ various biomarkers, including CD45, CD3ε, CD11b, Foxp3, IFN-γ, Cxcl11, Cxcl10, TNF-α, IL-23, MHC class II, CD80, CD86, and CD40.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	LAFACE, Drake, Maurice, WILLIAMS, Sybil, M., G, PINHEIRO, Elaine, HAN, Jin-Hwan, SEGHEZZI, Wolfgang
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Novel methods for selecting a patient with a cancer for treatment with a TIGIT antagonist are disclosed. The methods employ various biomarkers, including CD45, CD3ε, CD11b, Foxp3, IFN-γ, Cxcl11, Cxcl10, TNF-α, IL-23, MHC class II, CD80, CD86, and CD40.