METHOD OF ASSESSING GROWTH HORMONE DEFICIENCY IN HUMANS BY A MACIMORELIN CONTAINING COMPOSITION

The present invention relates to a method for measuring growth hormone level in a human or animal subject, including a method of assessing pituitary-related growth hormone deficiency in a human or animal subject. The method comprises oral administration of a macimorelin containing composition to sai...

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Bibliographische Detailangaben
Hauptverfasser:	MUELLER, Gilbert, SINDERMANN, Herbert, AMMER, Nicola, SACHSE, Richard
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	The present invention relates to a method for measuring growth hormone level in a human or animal subject, including a method of assessing pituitary-related growth hormone deficiency in a human or animal subject. The method comprises oral administration of a macimorelin containing composition to said subject, collecting one, two or three post-administration samples within a range of 25 to 95 minutes after administration from said subject, and comparing the level of growth hormone in the single sample, the two or three samples to a single threshold value. The method can be used for diagnosing pituitary-related growth hormone deficiency when the all levels of determined growth hormone are below the single threshold value.