FORMULATION

Provided is a formulation that can improve all of transdermal absorbability of an active ingredient, immediate effect in transdermal absorption, and reduction of skin irritation, to high levels. A formulation containing: a base; and a core-shell structure having a core portion containing an active i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KAWAMURA, Daichi, TONE, Saori, AKAMINE, Takayuki, OKAMOTO, Naoki, NAKAMURA, Yuuta, LI, Yan, MATSUMOTO, Izumi
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Provided is a formulation that can improve all of transdermal absorbability of an active ingredient, immediate effect in transdermal absorption, and reduction of skin irritation, to high levels. A formulation containing: a base; and a core-shell structure having a core portion containing an active ingredient and a shell portion containing a surfactant; in which the core portion is a solid, the surfactant contains a compound having two or more fatty acid bonds and a compound having one fatty acid bond, and a proportion of the compound having two or more fatty acid bonds in the surfactant is 5% by weight or more and 75% by weight or less.