COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS

COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS

Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular...

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Bibliographische Detailangaben
Hauptverfasser: BALKOVEC, James, M, CHEN, Zhi-Yong, TARI, Leslie, W, BORCHARDT, Allen, NONCOVICH, Alain, DO, Quyen-Quyen, Thuy, BRADY, Thomas, P, DOEHRMANN, Simon, LAM, Thanh, COLE, Jason, JIANG, Wanlong, BENSEN, Daniel, C
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).