RADIOPAQUE MULTI-ARMED POLYMERS AND COMPOSITIONS, SYSTEMS AND METHODS PERTAINING TO THE SAME

In some aspects, the present disclosure pertains to a polymer that comprises a plurality of polymeric arms, wherein a first portion of the polymeric arms each comprises a reactive end group and wherein a second portion of the polymeric arms each comprises a radiopaque aromatic moiety comprising a mo...

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Bibliographische Detailangaben
Hauptverfasser: DELANEY, JR., Joseph T, KOLSTE, Kolbein K, DYNDIKOVA, Tatyana
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:In some aspects, the present disclosure pertains to a polymer that comprises a plurality of polymeric arms, wherein a first portion of the polymeric arms each comprises a reactive end group and wherein a second portion of the polymeric arms each comprises a radiopaque aromatic moiety comprising a monocyclic or multicyclic aromatic structure having a plurality of radiopaque functional groups and a plurality of hydrophilic functional groups. In some aspects, the present disclosure pertains to systems comprising (a) a first composition comprising such a radiopaque polymer and (b) a second composition comprising a multifunctional compound that comprises reactive functional groups that are reactive with the reactive end group. In some aspects, the present disclosure pertains to crosslinked reaction products of (a) such a radiopaque polymer and (b) a multifunctional compound that comprises reactive functional groups that are reactive with the reactive end group.