STABILIZED VIRAL CLASS I FUSION PROTEINS

The present invention provides stable pre-fusion class I fusion protein in the pre-fusion conformation, comprising one or more mutations in the hinge-loop that is present between the base helix and the RR1.

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Bibliographische Detailangaben
1. Verfasser: LANGEDIJK, Johannes, Petrus, Maria
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention provides stable pre-fusion class I fusion protein in the pre-fusion conformation, comprising one or more mutations in the hinge-loop that is present between the base helix and the RR1.