IMMUNOSTIMULATORY LIPOPLEX, PHARMACEUTICAL COMPOSITION INCLUDING IMMUNOSTIMULATORY LIPOPLEX, AND USES THEREOF

IMMUNOSTIMULATORY LIPOPLEX, PHARMACEUTICAL COMPOSITION INCLUDING IMMUNOSTIMULATORY LIPOPLEX, AND USES THEREOF

An immunostimulatory lipoplex is provided. The immunostimulatory lipoplex includes a liposome and at least one immunostimulatory nucleic acid drug, and the immunostimulatory nucleic acid drug is complexed with the liposome. The liposome includes 40 to 85 mol% of cationic lipid, 10 to 50 mol% of chol...

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Hauptverfasser: Cheng, Felice, Wu, Ming-Hsi, Yu, Neng-Chang, She, Meng-Ping, Chen, Shih-Ta, Tu, Chia-Mu, Chang, Li-Wen, Wang, Hsiang-Ching, Li, Jheng-Sian, Liu, Chih-Peng
Format: Patent
Sprache:eng ; fre ; ger
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Cheng, Felice
Wu, Ming-Hsi
Yu, Neng-Chang
She, Meng-Ping
Chen, Shih-Ta
Tu, Chia-Mu
Chang, Li-Wen
Wang, Hsiang-Ching
Li, Jheng-Sian
Liu, Chih-Peng
description An immunostimulatory lipoplex is provided. The immunostimulatory lipoplex includes a liposome and at least one immunostimulatory nucleic acid drug, and the immunostimulatory nucleic acid drug is complexed with the liposome. The liposome includes 40 to 85 mol% of cationic lipid, 10 to 50 mol% of cholesterol, and 0.001 to 20 mol% of modified polyethylene glycol lipid. A pharmaceutical composition including the immunostimulatory lipoplex is also provided.
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HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title IMMUNOSTIMULATORY LIPOPLEX, PHARMACEUTICAL COMPOSITION INCLUDING IMMUNOSTIMULATORY LIPOPLEX, AND USES THEREOF
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