IMMUNOSTIMULATORY LIPOPLEX, PHARMACEUTICAL COMPOSITION INCLUDING IMMUNOSTIMULATORY LIPOPLEX, AND USES THEREOF

IMMUNOSTIMULATORY LIPOPLEX, PHARMACEUTICAL COMPOSITION INCLUDING IMMUNOSTIMULATORY LIPOPLEX, AND USES THEREOF

An immunostimulatory lipoplex is provided. The immunostimulatory lipoplex includes a liposome and at least one immunostimulatory nucleic acid drug, and the immunostimulatory nucleic acid drug is complexed with the liposome. The liposome includes 40 to 85 mol% of cationic lipid, 10 to 50 mol% of chol...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cheng, Felice, Wu, Ming-Hsi, Yu, Neng-Chang, She, Meng-Ping, Chen, Shih-Ta, Tu, Chia-Mu, Chang, Li-Wen, Wang, Hsiang-Ching, Li, Jheng-Sian, Liu, Chih-Peng
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An immunostimulatory lipoplex is provided. The immunostimulatory lipoplex includes a liposome and at least one immunostimulatory nucleic acid drug, and the immunostimulatory nucleic acid drug is complexed with the liposome. The liposome includes 40 to 85 mol% of cationic lipid, 10 to 50 mol% of cholesterol, and 0.001 to 20 mol% of modified polyethylene glycol lipid. A pharmaceutical composition including the immunostimulatory lipoplex is also provided.