THERAPEUTIC PROTEIN COMPOSITIONS AND METHODS

Compositions of the inventive concept provide a therapeutic protein with less than 2% contamination by the therapeutic protein in denatured form. Such compositions provide enhanced specific activity and improved stability on storage and/or in serum than corresponding therapeutic protein preparations...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RADTKE, Peter, ZURLO, Eugene, CURTIN, Dennis, BRILLHART, Kurt L
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Compositions of the inventive concept provide a therapeutic protein with less than 2% contamination by the therapeutic protein in denatured form. Such compositions provide enhanced specific activity and improved stability on storage and/or in serum than corresponding therapeutic protein preparations resulting from conventional isolation methods.